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Year : 2021  |  Volume : 21  |  Issue : 2  |  Page : 56-60

Systemic amyloidosis: A big masquerade of clinical symptoms with catastrophic consequences

Department of Medicine, Federal Medical Centre, Abeokuta, Nigeria

Correspondence Address:
Dr. A M Amusat
Department of Medicine, Federal Medical Centre, Abeokuta
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/njhs.njhs_31_20

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A case of a 52-year-old woman presented with non-specific symptoms: generalised weakness, loss of appetite and left leg pain of about a week duration. She later developed nephrotic syndrome, cardiomegaly with arrhythmias, adrenal insufficiency, cutaneous amyloid, with consolidation on chest X-ray and hepatomegaly. She had a renal biopsy that revealed renal amyloidosis. She was treated with thalidomide, bortezomib, methylprednisolone, ranitidine and allopurinol without significant improvement. Amyloidosis is a rare disease that requires a high index of suspicion. She may have responded if she had been diagnosed early, and hence, early diagnosis is a key in successful management.

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